The Role of Delayed Ocular Disorders of Mustard Gas on Catalase and Glutathione s-Transferase Activity
Trauma Monthly: 10 (4); 299-306 Article Type: Research Article
D, et al. The Role of Delayed Ocular Disorders of Mustard Gas on Catalase and Glutathione s-Transferase Activity,
Online ahead of Print
Objective : The aim of this study was to determine the enzymatic activity of catalase, glutathione s-transferase and protein concentration in serum and tear samples of patients and to compare the findings with normal samples. Material and Methods : We analyzed specific activity of catalase in tear and serum samples, specific activity of glutathione s-transferase in serum and protein concentration in tear and serum samples and compared the results in normal and patient groups. Results : There was statistically significant increase in protein concentration (P<0.001) and specific activity of catalase (P<0.05) in patient's serum samples as compared with normal serum samples. Conclusion : The role of hydrogen peroxide in ocular disease especially in cornea, imbalance of oxidant/antioxidant systems in serum, tear and ocular tissues is very important. More electrophoresis studies are necessary to determine the specific protein type that leads to total protein increase.
© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.