Effect of Allopurinol in Chronic Nonbacterial Prostatitis: A Double Blind, Randomized Clinical Trial
Trauma Monthly: 10 (2); 121-128 Article Type: Research Article
M. Effect of Allopurinol in Chronic Nonbacterial Prostatitis: A Double Blind, Randomized Clinical Trial ,
Online ahead of Print
Objective: The purpose of this study to evaluated a double blind randomized clinical trial effect of allopurinol in chronic nonbacterial prostatitis in comparison to the ofloxacine. Materials and Methods: Our cases (N=56) were randomly assigned to two groups: “interventional group” received alluporinol in addition to the routine antibiotic therapy with ofloxacin (n=27) and “control group” received placebo with ofloxacine (n=29). Patients’ scores based on the National Institute of Health Chronic Prostatitis Symptom Score and four glass test recorded before and after therapy in both groups. Results: The two groups were similar regarding outcome variables. In the first month of the study, a significant but similar improvement in symptom scores was observed in both groups. Conclusion: We did not find any advantage for allopurinol in management of chronic prostatitis versus placebo in patients receiving routine antibacterial treatment.
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