Evaluation of 50-gr Glucose Tolerance Test for Detection of Gestational Diabetes in Pregnant Women without Risk Factor
Trauma Monthly: 11 (2); 205-212 Article Type: Research Article
A. Evaluation of 50-gr Glucose Tolerance Test for Detection of Gestational Diabetes in Pregnant Women without Risk Factor,
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Aims. gestational (GDM) Diabetes is one of the diseases with serious Complications. About 50% of patients with known GDM are without risk factors for Diabetes Mellitus. We try to evaluate the 50-gr Glucose tolerance test (GTT) as a screening test in no risk factors women for early detection of GDM. Methods. In a Prospective longitudinal cohort study (a Process research), 246 pregnant women with no previous history of diabetes mellitus who sought prenatal care in Najmiyeh Obstetric clinic during 1380-83 were considered eligible. 50-g GTT performed between the 24 th and 28 th weeks of pregnancy. The 50-g GTT screening was considered positive when the one-hour post-intake glucose level was > 140 mg/dl. In these patients Oral GTT performed for diagnosis of gestational Diabetes. From 246 pregnant women suffer to GDM, 50 patient (20.3%) had one-hour post-intake glucose level was > 140 mg/dl that 11 patients those of them had at least 2 Glucose impaired characters for GDM diagnosis. In our study, prevalence of GDM was 4.4%. According to true positive (11 patients), False positive (39 patients), true negative (209 patients) and without False negative so Sensitivity and Specify were 100% and 84.6%. PPV and NPV were 22% and 100%. Results. Conclusion. prevalence of GDM and importance of Gestational Complications beside of our study results revealed the Low cost 50-g GTT screener test to be considered as an appropriate protocol for screening of GDM. Although other studies for approve of our results are necessary.
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