Efficacy of Topical Ophthalmic ProphyLaxis in Prevention of Ophthalmia Neonatorum
Trauma Monthly: 11 (2); 199-203 Article Type: Research Article
M, et al. Efficacy of Topical Ophthalmic ProphyLaxis in Prevention of Ophthalmia Neonatorum,
Online ahead of Print
Aims. Toevaluate the effect of topical efficacy of topical ophthalmic prophylaxis in prevention of ophthalmia neonatorum. Methods. In this random clinical control trial, ophtalmia neonatorum was investigated in one university center and the prophylactic effect of normal saline and ophthalmic erythromycin was compared with a group not receiving any prophylaxis. During July to December 2001, 1002 newborns were participated in the study. Ophthalmic prophylaxis started immediately after birth. The first group received ophthalmic erythromycin ointment (%0.5), in the second group neonates were distilled one drop of normal saline into each eye and the third group did not receive any prophylaxis. Within the first 10 days of life, conjunctivitis developed in 138 newborns (%13.8). About %29.7 of conjunctivitis cases were in erythromycin group, %31.9 in normal saline group and %38.4 were observed in no prophylaxis group. In general no significant difference was observed among 3 groups ( p >0.05). There was no case of gonococcal conjunctivitis (which in many cases results in blindness) in this study. Results. Conclusion. It seems prophylaxis is not required.
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