A Comparison of Propofol and Sodium Thiopental Effects on Mother and Neonate in Induction of Cesarean Section Anesthesia
Trauma Monthly: 11 (3); 285-292 Article Type: Research Article
January 1, 2006
January 1, 2006
L. A Comparison of Propofol and Sodium Thiopental Effects on Mother and Neonate in Induction of Cesarean Section Anesthesia,
Online ahead of Print
Introduction In the current study, we intended to evaluate the effects of propofol and thiopental sodium on APGAR and neurobehavioral scores of the neonates and the variation of hemodynamic indices and their possible side effects on the mothers. Material and Methods. In this double blind randomized clinical trial, 50 patients with ASA class I undergoing cesarean section were randomly separated into two equal groups. For anesthesia in the first group thiopental 5 mg/kg and in the second group propofol 2 mg/kg were used. Time of induction of anesthesia, time of child birth, time of uterus incision and duration of surgery were recorded. Neonates APGAR scores in 1 and 5 minutes and neurobehavioral examinations in 8-12 hours after section were detected. The results were compared using SPSS software and t-test. Results. Time of uterus incision, time of child birth and duration of surgery did not have any significant difference in the two groups. No significant difference was detected in the hemodynamic variations in the mothers of the two groups. No significant difference was detected in the APGAR scores in 1 minute (p=0.602) and 5 minutes (p=0.322) in the neonates of the two groups and no significant difference was detected in the mean of neurobehavioral scores of two groups (p=0.546). Conclusion. Considering the absence of any differences in the APGAR scores and neurobehavioral scores in the neonate of the two groups, this conclusion can be driven that propofol is the suitable alternative for induction anesthesia in cesarean section.
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