Comparison of local recurrence, metastasis and survival rate between two surgical approaches in clinical stage I and II in breast cancer
Trauma Monthly: 14 (2); 89-94 Article Type: Research Article
S M, Mofid
H A, Mehmannavaz
M. Comparison of local recurrence, metastasis and survival rate between two surgical approaches in clinical stage I and II in breast cancer,
Online ahead of Print
Aims:In patients with stage I and II of breast cancer, two common approaches are used: breast conservative surgery (BCS) and modified radical mastectomy (MRM). This study compared some variables between these methods.
Materials & Methods: In a cross-sectional descriptive analytic study, medical records of 242 females with stage I and II of breast cancer were analyzed, retrospectively. These patients were operated by two types of BCS and MRM surgery. Follow-up was performed via examination or telephone call. Frequency and mean of variables measured. Life table, caplan-mayer and cox regression test used to evaluate the survival rate.
Results: 109 patients (45%) were undergone BCS and 133 patients (55%) MRM. The mean age of patients in BCS was 47.2±10.4 and in MRM was 49.4±11.8 (p=0.5). There was no significant difference in locoregional recurrence (BCS 2.5%, MRM 3.2% p=0.8), 1-year survival rate (both 100%) and 3-year survival rate (BCS 93% and MRM 94%) between two groups. However, metastasis was significantly lower in BCS (7.3%) group than MRM (18%) group (p=0.01).
Conclusion:BCS method is not increasing the risk of locoregional recurrence and metastasis and decreasing the survival rate, so considering cosmetic advantages, BCS can be performed safely.
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