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Trauma Mon. 2019;24(4): e90745.
doi: 10.5812/traumamon.90745

Scopus id: 85067252464
  Abstract View: 459
  PDF Download: 159

Research Article

Novel Fracture Improvements via Vitamin D Supplementation

Abolfazl Kazemi 1, Masoud Shayesteh Azar 1 * , Mehran Razavipour 1, Salman Ghaffari 1, Mohammad Khademloo 2, Hosein Azade 3

1 Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran
2 Department of Community Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
3 Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
* Corresponding author: Associate Professor of Orthopedic Surgery, Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Email: Email: mshayestehazar@yahoo.com

Abstract

Background: Distal radius fracture (DRF) is one of the most common upper limb fractures, which is associated with osteoporosis and vitamin D deficiency, especially in old adults.

Objectives: The aim of this study was to evaluate the effect of supplementary vitaminD on grip strength, pinch power, pain intensity, and DASH score in post-menopausal females after distal radius fractures.

Methods: Fifty-two post-menopausal women with distal radius fractures were enrolled in a randomized single-blinded multicenter trial from January 2015 to January 2016 (IRCT registration number: IRCT20160830029603N7). Patients with pre-operative serum vitamin D level of 30 to 100 ng/mL were enrolled in the study. Patients were divided into two randomized groups including groups with and without supplementation of vitamin D [25 women in intervention group (50,000 IU supplementary vitamin D, every 4 weeks for 6 months) and 27 women in placebo group]. Grip strength, pinch power, pain intensity, and DASH score pre-operatively and at three and six months after the surgery were measured; the obtained data were analyzed using SPSS version 16.

Results: The subjects’ mean age in vitamin D supplemented and placebo group was 57.98 ± 7.15 and 59.15 ± 8.03, respectively. The mean grip strength of patients in vitamin D supplemented group was significantly higher than the placebo group on both the third and sixth months (P = 0.011 and P = 0.003, respectively). The pinch power was significantly increased on the sixth month compared to the third month in patients with revised vitamin D supplementation (1.32 ± 2.14 and 0.67 ± 0.96 respectively, P = 0.0001). There was no statistically significant difference between the two groups in terms of mean VAS and DASH scores at the end of the study (P = 241, P = 0.665, respectively).

Conclusions: Vitamin D supplementation was significantly helpful in improving grip strength recovery in post-menopausal women after distal radius fracture, however, no significant differences were observed in supplementation of vitamin D on pinch power and pain intensity after distal radius fractures.

Keywords: Vitamin D, Distal Radius, Fracture, Post-Menopausal, Wrist Function
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Submitted: 16 Feb 2019
Accepted: 07 Mar 2019
First published online: 04 May 2019
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